What won't happen? When you talk to someone at a depression hotline/helpline, it's important to remember that this isn't the same as talking to a psychotherapist or counselor. The person you talk to at a helpline isn't able to give you medical advice or therapy. He or she can give you general advice or tips for coping with depression, but won't tell you what to do. Talking to someone at a depression helpline isn't a replacement for therapy.

With depression there are different problems, that goes from denial of the fact or of the trigger that originates it, to the lack of understanding and willingness to accept that the world will not turn upside down to accommodate ones wishes, easily. So, the more effective we are in hiding, from ourselves, the reason that depress us, and the greater the believe that the world and the people around us should adjust to our needs, the more difficult it is to get out of the depressing state.
A week after spending the night awake with Angelina, I call Benedetti to check her progress. He tells me that after the third sleep deprivation, she experienced a full remission in her symptoms and returned to Sicily with her husband. That week, they were due to be marking their 50th wedding anniversary. When I’d asked her if she thought her husband would notice any change in her symptoms, she’d said she hoped he’d notice the change in her physical appearance.
Des conséquences à relativiser toutefois. Lorsque la dépression est diagnostiquée après la naissance, la maman, peut, "malgré son état, avoir les bons gestes et apporter de la sécurité à son bébé. Sans s'en occuper, elle peut aussi lui dire qu'elle est présente. D'autres, sont dans une grande indisponibilité émotionnelle… l’enfant sent tout cela" explique Françoise Molénat.

Not that it has hurt the market. At last count, about 12% of Americans took antidepressants. Global revenue for antidepressants was about $14.5 billion in 2014 and is projected to grow to nearly $17 billion over the next three years. Clinical depression affects 6.7% of U.S. adults, or about 16 million people, and a growing number of children and teenagers too. It’s the leading cause of disability in the world, costing the U.S. economy alone $210 billion a year in lost productivity, missed days of work and care for the many physical and mental illnesses related to depression, like anxiety, posttraumatic stress disorder, migraines and sleep disorders.


La vraie question concerne les antidépresseurs. Les inhibiteurs sélectifs de la recapture de la sérotonine (ISRS) à courte demi-vie sont le traitement de premier choix, mais les données sont encore limitées.9,10 Les profils de sécurité de ces molécules sont à considérer avec prudence. L’exposition est associée à une proportion de malformations congénitales comparable à celle de la population générale mais on a rapporté un risque d’hypertension pulmonaire durable chez le nouveau-né de mères traitées. Notamment, il est important d’adapter la posologie en fonction de l’évolution de la clairance hépatique et rénale au cours de la grossesse et de la période post-partum. Pour le nouveauné, des complications postnatales légères et transitoires, comme irritabilité, troubles du sommeil, hyperbilirubinémie, tremblements ont été décrites.

Since 2006, dozens of studies have reported that it can also reverse the kind of severe depression that traditional antidepressants often don’t touch. The momentum behind the drug has now reached the American Psychiatric Association, which, according to members of a ketamine task force, seems headed toward a tacit endorsement of the drug for treatment-resistant depression.
Nevertheless, the available evidence base for treatment is limited, since most participants in clinical trials are recruited by advertisement rather than from representative practices, and they are often selected to have few comorbid disorders, either medical or psychiatric. In addition, those with chronic depression or current suicidal ideation are excluded.1,4 These uncomplicated and “pristine” participants are unlike typical patients seen by primary care physicians or psychiatrists.

Les femmes sont plus vulnérables à la dépression pendant la grossesse et pendant les semaines et les mois suivant l’accouchement. Pendant la grossesse, les changements hormonaux peuvent agir sur les produits chimiques du cerveau et provoquer la dépression et l’anxiété. Il arrive que les femmes ne se rendent pas compte qu’elles sont déprimées. Elles peuvent penser présenter des symptômes de la grossesse ou « avoir les bleus », que bien des femmes ressentent après l’accouchement.
Even so, interest in the processes underpinning chronotherapy is beginning to spread. “Insights into the biology of sleep and circadian systems are now providing promising targets for treatment development,” says Geddes. “It goes beyond pharmaceuticals – targeting sleep with psychological treatments might also help or even prevent mental disorders.”
Une étude* a ainsi montré que 24 % des enfants âgés de 1 an nés de mère dépressive manifestent des troubles de l'interaction. Plus récemment, il a été montré que 40 % des enfants de parents ayant présenté des troubles affectifs autour de la naissance reçoivent un soin psychiatrique au cours de leur vie d'adulte. Ces constatations soutiennent l'intérêt d'interventions thérapeutiques multiformes auprès du couple que forme une mère dépressive et son bébé.
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