第二,加强营养。良好的饮食结构可以使我们身体机能得到很大的提高,抑郁症患者在日常治疗过程中,除了按时吃药以外日常饮食也是非常需要注意的,有些食物对改善抑郁有较大的益处。如深海瑰宝——鱼。鱼体内的成分Omega-3脂肪酸是天然的抵抗抑郁症的瑰宝。常食用海鱼,会明显降低抑郁症的发病、缓解抑郁情绪。还有快乐水果——香蕉、葡萄柚、樱桃等,其中,香蕉有一种可以令人兴奋和提高情绪精神的物质——生物碱,非常有利于增加人体大脑血清素。血清素的增加有助于,神经细胞的传递,提高大脑神经系统,这也是抑郁症的食疗方法之一。心情法宝——大蒜、南瓜。大蒜和南瓜都是帮助人们恢复心情的法宝。常吃大蒜人们就不会感觉劳累和焦虑,对急躁情绪有所缓解。南瓜中的维生素可以帮助人体补充B6和铁,南瓜被称为天然的人体汽油。合理的饮食对人体本身产生积极因素,都是对抗抑郁的好东西,但是我们还是要注意有些食物不适合患者,如酒、浓茶、咖啡、油炸辛辣等食物,尽可能避免食用。
As clinicians, we routinely make critical decisions for our patients with depression. Because of the uncertainty of factors that affect diagnosis and treatment, clinicians may find an objective, quick measurement tool helpful. Measurementbased care (MBC) provides specific and objective information on which to base clinical decisions and should therefore enhance quality of care and treatment outcomes. (1-3) MBC rests on these assumptions. * Compared with general questions that are typically asked during a patient evaluation, specific measurements (administered by clinicians or self-reported by patients) provide more accurate information on which to establish a diagnosis, assess treatment outcomes, and modify treatments. * Patients who complete these measurement tests will better understand their disorder and treatment effects, which will enable them to better manage their depression. * Medical records that include the results of specific measurements will assist subsequent clinicians in understanding the results of prior treatments. * The routine use of the same measurements in practice and clinical research studies will help clinicians translate research findings into their own practices. * For most outpatients with depression, self-report methods are available that are free and that take little time and effort. Diagnostic measurements Researchers have used criterion-based diagnostic methods for years. After DSM-III was introduced in 1980, the Structured Clinical Interviews for DSM-III (SCID) (and later for DSMIV) were developed to obtain lifetime diagnoses. (4,5) Briefer structured interviews were then developed, including the Mini-International Neuropsychiatric Interview (MINI), which assesses only current diagnoses, and the MINI-Plus, which elicits information about current and past diagnoses. (6-8) The MINI takes 30 to 40 minutes to administer, while the MINI-Plus may take up to 60 minutes. Studies have shown that structured or semistructured interviews provide more accurate diagnoses than typical practice. For example, clinically rendered diagnoses were compared with those made based on SCID results. (9) Major diagnostic differences were found in 40% of outpatients with clinical diagnoses of schizophrenia or bipolar or major depressive disorders. In addition, when clinicians were provided with a diagnosis that was determined using SCID, they changed the chart diagnosis in a substantial proportion of cases and prescribed fewer medications. (10) Symptom measurements Once a diagnosis has been made and therapy has been initiated, the regimen must often be modified because of intolerance, adverse effects, or other less-than-desirable symptomatic outcomes. Medication and somatic therapies are typically aimed at treating symptoms, but psychotherapy and disease self-management may also address other aspects of treatment (eg, medication adherence, social/occupational function, self-esteem). The Texas Medication Algorithm Project (TMAP) and the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) studies showed that diligent assessment of symptoms and adverse effects enhances outcomes. (11-14) The goal of therapy for depression is symptom remission and, ultimately, sustained remission and functional recovery. (15) Most patients require more than 1 treatment revision (eg, altered dosage, treatment, or delivery). When implementing guideline-driven or evidencebased care, initial treatment is continued until remission or maximal symptom improvement is obtained or until the patient cannot tolerate the regimen. Thereafter, the dosage or type of treatment may...

Brintellix通用名Vortioxetine,是一种调节和促进血清素分泌类的药物,属于非典型性抗抑郁症药物,它的机制目前还不完全清楚,但是发现它同时起到血清素再摄取抑制剂、去甲肾上腺素再摄取抑制剂、5-HT 1A受体激动剂、5-HT 1B受体部分激动剂等功能。武田制药声称,这款药物是目前唯一通过这种综合性的功能来促进血清素水平的药物,虽然每一种功能对其发挥抗抑郁作用的贡献有多大,目前为止还不是很清楚,此药除了能够改善患者的情绪外,临床研究显示还能改善认知功能,对于目前市场上销售的抗抑郁症药物来说,这可以称得上是一种具有进步性的药物。此药由武田和丹麦的灵北制药公司共同销售,在这笔交易中武田支付灵北制药4000万美元的先期付款,另外总计高达3.45亿美元的里程碑付款。2013年先后在美国和欧盟上市,预测2017年销售额8.45亿美元, 2021年销售额为17.5亿美元。
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